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Lecture Notes in German (Skripten):
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LIST OF PUBLICATIONS
Cardiovascular Pathophysiology (40 pages in pdf)
Renal Pathophysiology (50 pages in pdf)
Nutrition and Digestion (29 pages in pdf)
Hepatic pathophysiology (14 pages in pdf)
Carcinogenesis (45 pages in pdf)
Bone Metabolism (17 pages in pdf)
Pathophysiology of Skeletal Muscle (11 pages in pdf)
ORIGINAL ARTICLES
K. Ecker, A. Lorenz, F.
Wolf, C. Ploner, G. Böck, T. Duncan, S. Geley and A. Helmberg (2009):
A Ras recruitment screen identifies ZKSCAN4 as
a glucocorticoid receptor interacting protein.
J. Mol. Endocrinol. 42:
105-117.
E. Presul, S. Schmidt, R. Kofler and A. Helmberg (2007):
Identification, tissue expression, and glucocorticoid responsiveness of
alternative first exons of the human glucocorticoid receptor.
J. Mol. Endocrinol. 38:
79-90.
B. Henderson, M. Kind, G. Böck, A. Helmberg
and G. Wick (2006):
Gene expression profiling of human endothelial cells exposed to 50-Hz
magnetic fields fails to produce regulated candidate genes.
Cell Stress Chaperones. 11: 227-232.
P. Obexer, U. Certa,
R. Kofler and A. Helmberg (2001):
Expression profiling of glucocorticoid-treated T-ALL cell lines: rapid
repression of multiple genes involved in RNA-, protein- and nucleotide
synthesis.
Oncogene 20: 4324-4336.
M. Tonko,
M. J. Ausserlechner, D. Bernhard, A. Helmberg and R. Kofler (2001):
Gene expression profiles of proliferating vs. G1/G0 arrested human
leukemia cells suggest a mechanism for glucocorticoid-induced apoptosis.
FASEB J. 15, 693-699.
M. Löffler, M. J. Ausserlechner, M. Tonko, B. L.
Hartmann, D. Bernhard, S. Geley, A. Helmberg and R. Kofler (1999):
c-Myc does not prevent glucocorticoid-induced apoptosis of human leukemic lymphoblasts.
Oncogene 18, 4626-4631.
S. Geley,
K. Kapelari, K. Jöhrer, M.
Peter, J. Glatzl, H. Vierhapper,
S. Schwarz, A. Helmberg, W. G. Sippell, P. C. White and R. Kofler (1996):
CYP11B1 mutations causing congenital adrenal hyperplasia due to
11ß-hydroxylase deficiency.
J. Clin. Endocr. Metab. 81, 2896-2901.
N. Auphan, J. A. Didonato,
C. Rosette, A. Helmberg and M. Karin (1995):
Molecular basis for immunosuppression by glucocorticoids: Inhibition of NFkB activity through induction of IkB synthesis.
Science 270, 286-290.
A. Helmberg, N. Auphan, C. Caelles,
M. Karin (1995):
Glucocorticoid-induced apoptosis of human leukemic cells is caused by the repressive function of the glucocorticoid
receptor.
EMBO J. 14: 452-460.
Caelles, A. Helmberg, M. Karin (1994):
p53-Dependent apoptosis
is not mediated by transcriptional activation of p53-target genes.
Nature 370: 220-230.
A. Helmberg, B. Ausserer, R. Kofler (1992):
Frameshift by insertion of two base pairs in codon 394 of CYP11B1 causes
congenital adrenal hyperplasia due to steroid 11-beta-hydroxylase deficiency.
J. Clin. Endocrinol. Metab. 75: 1278-1281.
A. Helmberg, M.-T. Tusie-Luna, M. Tabarelli, R. Kofler, P. C. White
(1992):
R339H and P453S: CYP21 mutations associated with nonclassic steroid 21-hydroxylase deficiency that are not apparent gene conversions.
Mol. Endocrinol. 6: 1318-1322.
A. Helmberg, M. Tabarelli, M. A. Fuchs, E. Keller, G. Dobler, I. Schnegg, D. Knorr, E. Albert, R. Kofler (1992):
Identification of molecular defects causing congenital adrenal
hyperplasia by cloning and differential hybridization of polymerase chain
reaction -amplified 21-hydroxylase (CYP21) genes.
DNA Cell Biol. 11: 359-368.
H. Kofler, I. Schnegg, S. Geley, A. Helmberg,
J. M. Varga, R. Kofler (1992):
Mechanism of allergic cross-reactions-III. cDNA cloning and variable-region sequence analysis of two IgE antibodies specific
for trinitrophenyl.
Mol. Immunol. 29: 161-166.
G. Kroemer,
A. Helmberg, A. Bernot, C. Auffray,
R. Kofler (1991):
Evolutionary relationship between human and mouse immunoglobulin kappa
light chain variable region genes.
Immunogenetics 33: 42-49.
A. Helmberg, R. Fässler, S. Geley, K. Jöhrer, G. Kroemer, R. Kofler
(1990):
Glucocorticoid-regulated gene expression in the immune system: analysis
of glucocorticoid-regulated transcripts from the mouse macrophage-like cell
line P388D1.
J. Immunol.
145: 4332-4337.
R. Strohal,
A. Helmberg, G. Kroemer, R. Kofler (1989):
Mouse Vk gene classification by nucleic acid
sequence similarity.
Immunogenetics 30: 475-493.
A. Helmberg, G. Böck,
H. Wolf, G. Wick (1989):
An orally administered bacterial immunomodulator primes rabbit neutrophils for increased oxidative burst in response to
opsonized zymosan.
Infect. Immun. 57: 3576-3580.
T. F. Schulz, A.
Helmberg, M. Hosp, A. Petzer, B. Föger,
M. P. Dierich (1985):
Enzyme-linked immunoassay to monitor the purification of, and to screen
for monoclonal antibodies against, C3b receptor.
Complement 2: 219-229.
REVIEWS
A. Helmberg (2001):
DNA-microarrays: Novel techniques to study aging and guide gerontologic medicine.
Exp. Gerontol. 36:
1189-1198.
N. Auphan, J. A. Didonato,
A. Helmberg, C. Rosette, M. Karin (1997):
Immunoregulatory genes and
immunosuppression by glucocorticoids.
Arch. Toxicol. Suppl. 19: 87-95.
F. Saatcioglu, A. Helmberg, M. Karin (1994):
Modulation of immune function through interference between nuclear
receptors and AP-1.
Fund. Clin. Immunol. 2: 27-36.
A. Helmberg (1992):
Twin genes and endocrine disease: CYP21 and CYP11B genes.
Acta endocrinol. 129: 97-108.
R. Kofler, S. Geley, H. Kofler, A. Helmberg (1992):
Mouse variable region gene families: complexity, polymorphism and use in
non-autoimmune responses.
Immunol. Rev. 128:
1-17.
BOOK CHAPTER
A. Helmberg (2007):
Chapter 13,
"Maligne Neoplasien" in
"Pathophysiologie- Molekulare, zelluläre und systemische Grundlagen von
Krankheiten ". Eds. Siegfried Schwarz, Othmar Förster, Meinrad Peterlik, Konrad Schauenstein and Georg Wick.
Maudrich, Vienna
2007.
PUBLISHED LETTERS TO THE
EDITOR AND COMMENTS
R. Kofler, A. Helmberg (1991):
Comment to the article "High frequency expression of S107 Vh genes by peritoneal B cells of B10.H-2aH-4bP/WTS
mice".
J. Immunol.
146: 1385.
R. Kofler, A.
Helmberg (1991):
Comment to the article "A new Igk-V gene
family in the mouse"
Immunogenetics 34: 139-140.
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